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Cyber at the Top: Evolving Zero Trust for the AI Era


Posted on by Hugh Thompson

Recently, I heard someone claim on a podcast, “Zero Trust is dead.” I couldn’t disagree more. Zero Trust remains one of the most enduring and widely used concepts in cybersecurity. Every year, as we analyze thousands of submissions for RSAC™ Conference, it consistently dominates the word cloud. It’s everywhere, and for good reason.

In the latest episode of Cyber at the Top, I had the opportunity to speak with Alissa “Dr. Jay” Abdullah, Deputy Chief Security Officer at Mastercard and the company’s resident AI futurist. Our conversation made one thing clear: Zero Trust isn’t fading away; it’s evolving. As AI reshapes how organizations operate and how adversaries attack, Zero Trust has become even more essential. Dr. Jay shared how Mastercard applies Zero Trust in practice, why AI has raised the stakes, and what cyber leaders should prioritize as they begin or mature their Zero Trust journey.

Evolution of Zero Trust topics at RSAC Conference since 2021

  The RSAC™ Cybersecurity Atlas: Map of Topics, 2021-2025 analyzes data from the RSAC Call for Submissions process to visualize changes to the community’s priorities over time. Below are a few examples of the evolution of Zero Trust-related topics since 2021:CISO ON TOP JAN 16


CISO 2 ON TOP
Cyber Atlas tool
 in the RSAC™ Community Platform.

 

Defining Zero Trust at scale

A walk across the Expo floor at RSAC Conference will inevitably surface countless vendors promoting Zero Trust solutions, but as Dr. Jay emphasized, Zero Trust is not a product. It’s a principle and a fundamental shift in mindset. “It’s more important now than it’s ever been,” she explained. “There is no implicit trust. We have to be in the mindset of Zero Trust because AI is a game changer.”

At Mastercard, that mindset translates into enforcing least privilege, ensuring users have access only to what they need, for exactly as long as they need it. This discipline becomes even more critical as AI systems move faster, automate decisions, and operate at a scale humans simply can’t match.

Dr. Jay also made an important point: Zero Trust shouldn’t live solely in the cybersecurity domain. It’s a mindset worth extending to non-profits, small businesses, and even conversations with family members. The more broadly we understand and adopt Zero Trust principles, the better positioned we are to ensure that innovation and security advance together.

Why Zero Trust is critical in the age of AI

Zero Trust has been a recurring theme in RSAC Conference submissions for many years, long before topics like generative and agentic AI became part of the mainstream conversation. While AI-related terms may dominate headlines today, that doesn’t diminish the relevance of Zero Trust. In fact, it makes it non-negotiable.

AI accelerates everything, including both innovation and attack. Organizations are using AI to scale operations, increase efficiency, and unlock new capabilities. At the same time, adversaries are leveraging AI to discover vulnerabilities faster, evade detection, and launch more sophisticated attacks. According to Dr. Jay, Zero Trust helps eliminate the blind spots AI can introduce. It provides the guardrails organizations need to harness innovation without sacrificing security, ensuring that trust is continuously verified rather than assumed.

Getting started on the Zero Trust journey

For leaders wondering where to begin, Dr. Jay’s advice offers a practical approach. Start with identity. Before you can trust anything, you need to verify it. That means moving beyond traditional MFA and layering additional signals, such as biometrics, behavioral context, and continuous authentication. Visibility is also important: you can’t protect what you don’t know exists, so understanding your assets, users, and data flows is critical. From there, automation becomes a force multiplier, helping security teams keep pace in an AI-driven environment. As Dr. Jay put it, “AI will expose any vulnerabilities or bad habits.”

One of the most compelling ideas I took away from our conversation was treating AI itself as an identity. Models and agents should be governed with the same principles as human users to ensure clear accountability, least privilege, and continuous oversight. Framing it this way helps organizations understand the risk and the responsibility that comes with deploying AI at scale. Above all, remember that Zero Trust isn’t a one-time technology project; it’s a cultural shift. Focus on quick wins, build momentum, and embed the mindset into your organization’s DNA. If you start with identity and access, you’re already well on your way.

 

To hear more details from our conversation and to continue learning from Dr. Jay, listen to the full podcast episode or watch the video here.

 

Contributors
Hugh Thompson

Executive Chairman & RSAC Conference Program Committee Chair, RSAC

Blogs posted to the RSAConference.com website are intended for educational purposes only and do not replace independent professional judgment. Statements of fact and opinions expressed are those of the blog author individually and, unless expressly stated to the contrary, are not the opinion or position of RSAC™ Conference, or any other co-sponsors. RSAC Conference does not endorse or approve, and assumes no responsibility for, the content, accuracy or completeness of the information presented in this blog.


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